The amplification setting in the RANGE-TAB represents the hardware amplification value of the amplifier that you are setting. The possible settings for this amplification can be different for different types of amplifiers (i.e. 8CHUNI modules or EEG modules).
With this amplification setting, the full scale input is defined.

Full scale input = 2,5 Volts / Amplification factor

The MUL and DIV factors in the SCALING-TAB are used as scaling factors to re-calculate "measured AD converter values" to physical units (i.e. Lumen, Bar, Meters, Feet). These values are shown when displaying the channel in the Columbus software. In combination with the offset value, it is possible to calibrate every sensor in his way. The MUL factor is used as Multiplier and the DIV factor as Divisor.

Example:
We want to connect a pressure sensor to one of the channels of the 8CHUNI module. The pressure sensor has a sensitivity of 41.700uV/mmHg, according to the manual. We want to measure pressure from +300mmHg to -300mmHg.
How do we need to set the amplifier settings?

The Manual and difficult way:
First we calculate the required Amplification factor and set this accordingly.

Amplification factor = 2,5 /600mmHg = 2,5 / 0,02502Volts = 99,9

The AD converter ranges from 0-4095, representing the full range. Because we want to measure symmetrically (0 in the middle), we set the "offset settings" to "Manual set" and "Symmetric". The offset value is set to "2048", the middle of the AD converter range.
We want 4096 AD values to represent 600mmHg, so we need to multiply each AD value with 600/4096 to get the right mmHg value.
The MUL factor now is 600 and the DIV factor is 4096!

When editing this we can see it reflected in the settings-tab.

The Automatic and easier way:
First we calculate the required Amplification factor again and set this accordingly in the RANGE TAB.

Now, in the RANGE-TAB, we set the "Display unit" to ... and "User unit" to "mmHg".
We set the "Sensitivity" to "41,7uV/mmHg".

Now, the SCALING-TAB is reflecting automatically the right values. We can fine tune the offsett, MUL and DIV values to calibrate the sensor even more accurately if needed.